Targeting both

Inflammation and

Mitochondrial Dysfunction

for the treatment of Diseases

with high unmet need

Unlocking the Full Therapeutic Value of Natural Cell Protection Pathways

OMEICOS is focused on developing therapies that have the potential for a significant impact on cardiovascular, inflammatory and mitochondrial diseases with high unmet need. Our pipeline is based on our proprietary approach to target one of nature’s most important cell-protective pathways and industry-leading knowledge of omega-3 fatty acid metabolism and biology.

OMEICOS lead compound, OMT-28, has recently completed a double-blinded, placebo-controlled, multi-center Phase 2 clinical trial in patients suffering from atrial fibrillation. OMT-28 proved its excellent safety and tolerability profile, already shown in Phase I with 75 healthy volunteers.

In addition, the study demonstrated a significant positive effect on a number of inflammatory biomarkers, among them IL-6 and GDF-15, the strongest independent predictors of mortality and disease progression in cardiovascular disease.

The company is planning a robust clinical proof-of-concept study to confirm OMT-28’s broad anti-inflammatory effect and to leverage the validated link between reduction of CV inflammation and significant reduction of adverse events in patients with Coronary Artery Disease.

OMEICOS has also demonstrated the positive effect of OMT-28 in mitochondrial dysfunction and plans for a proof-of-concept clinical study in myopathy/cardiomyopathy in patients with mitochondriopathies.

In addition, OMT-28 has shown potential for the application to other disease areas such as ophthalmology.

Latest Press Release

September 18, 2023
OMEICOS Therapeutics Provides Update on PMD-OPTION Phase 2a Clinical Study Evaluating OMT-28 in Primary Mitochondrial Disease
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Upcoming Events

March 18 - 20, 2024
Mitochondrial Medicine – Therapeutic Development
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