Acute Respiratory Distress Syndrome ARDS: OMT-28 protects against LPS induced lung injury in mice Tsubouchi et al. Eur J Pharmacol 2025
VISIT
Cardioprotective Properties of OMT-28
Kranrod et al. JBC 2024
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Pulmonary Hypertension: Omega-3 epoxyeicosanoids counteract development of PH
Moriyama et al. Nature Comm 2022
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Endotoxemia: OMT-28 amerliorats endotoxemia
Shikuma et al. Front Immunol 2022
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Heart Failure: Mitochondrial Dysfunction and Inflammaging: Protective Roles of CYP-Derived Epoxylipids
Keshavarz-Bahaghighat et al. Cells 2020
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Atrial Fibrillation: Assessment of OMT-28 in patients with persistent atrial fibrillation: Rationale and design of the PROMISE-AF phase II study
Berlin et al. Int J Cardiol Heart Vasc 2020
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Review: Therapeutic potential of omega-3 fatty acid-derived epoxyeicosanoids in cardiovascular and inflammatory diseases
Schunck et al. Pharmacol Ther 2018
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Ophtalmology, wetAMD: 17,18-EEQ and stable synthetic analog C21 reduce chorideal neovascularization via a immunomodulatory mechanism of action
Hasegawa et al. PNAS 2017
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Ophthalmology, wetAMD: 17,18-EEQ as active EPA metabolite, mediating reduction of chorideal neovascularization
Yanai et al. PNAS 2013
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